13F holdings as of 2026-03-31 · vs 2025-12-31 · long US-listed positions only
| # | Holding | Shares | Value | % of 13F | QoQ Δ | |
|---|---|---|---|---|---|---|
| 1 | RVMDREVOLUTION MEDICINES INC | TRIM | 1.2M | $117.6M | 6.9% | +$11.3M |
| 2 | LLYELI LILLY & CO | TRIM | 99K | $90.8M | 5.4% | -$22.5M |
| 3 | MDGLMADRIGAL PHARMACEUTICALS INC | ADD | 171K | $89.5M | 5.3% | +$8.2M |
| 4 | MIRMMIRUM PHARMACEUTICALS INC | ADD | 811K | $74.9M | 4.4% | +$14.7M |
| 5 | ARGXARGENX SE | TRIM | 99K | $71.9M | 4.2% | -$14.9M |
| 6 | RYTMRHYTHM PHARMACEUTICALS INC | TRIM | 690K | $60.0M | 3.5% | -$14.4M |
| 7 | INSMINSMED INC | TRIM | 314K | $51.4M | 3.0% | -$4.2M |
| 8 | ASNDUSDASCENDIS PHARMA A/S | TRIM | 194K | $44.4M | 2.6% | +$979K |
| 9 | XENEXENON PHARMACEUTICALS INC | TRIM | 763K | $44.4M | 2.6% | +$9.1M |
| 10 | TVTXTRAVERE THERAPEUTICS INC | TRIM | 1.5M | $43.9M | 2.6% | -$40.5M |
| 11 | KYMRKYMERA THERAPEUTICS INC | 497K | $41.4M | 2.4% | +$2.7M | |
| 12 | PENPENUMBRA INC | 121K | $39.6M | 2.3% | +$2.1M | |
| 13 | ISRGINTUITIVE SURGICAL INC | 82K | $37.8M | 2.2% | -$8.6M | |
| 14 | SRRKSCHOLAR ROCK HLDG CORP | ADD | 740K | $36.4M | 2.1% | +$4.1M |
| 15 | ELVNENLIVEN THERAPEUTICS INC | ADD | 827K | $32.4M | 1.9% | +$20.1M |
| 16 | BSXBOSTON SCIENTIFIC CORP | ADD | 515K | $32.3M | 1.9% | -$5.7M |
| 17 | IRTCIRHYTHM HOLDINGS INC | ADD | 262K | $30.9M | 1.8% | -$10.8M |
| 18 | GPCRSTRUCTURE THERAPEUTICS INC | TRIM | 640K | $30.9M | 1.8% | -$21.2M |
| 19 | AGIOAGIOS PHARMACEUTICALS INC | 799K | $27.0M | 1.6% | +$5.3M | |
| 20 | RAREULTRAGENYX PHARMACEUTICAL IN | TRIM | 1.2M | $25.5M | 1.5% | -$3.6M |
| 21 | ALNYALNYLAM PHARMACEUTICALS INC | ADD | 74K | $24.5M | 1.4% | -$3.8M |
| 22 | COGTCOGENT BIOSCIENCES INC | TRIM | 624K | $24.0M | 1.4% | -$6.1M |
| 23 | THCTENET HEALTHCARE CORP | 125K | $23.6M | 1.4% | -$1.3M | |
| 24 | DXCMDEXCOM INC | ADD | 356K | $22.3M | 1.3% | -$719K |
| 25 | CLDXCELLDEX THERAPEUTICS INC NEW | TRIM | 650K | $20.6M | 1.2% | +$1.8M |
| 26 | VERAVERA THERAPEUTICS INC | TRIM | 504K | $20.3M | 1.2% | -$8.5M |
| 27 | NBIXNEUROCRINE BIOSCIENCES INC | ADD | 150K | $19.8M | 1.2% | +$2.0M |
| 28 | ACLXGBXARCELLX INC | 170K | $19.5M | 1.1% | +$8.4M | |
| 29 | NEWAMSTERDAM PHARMA COMPANY | ADD | 589K | $18.8M | 1.1% | -$699K |
| 30 | PHARVARIS N V | ADD | 646K | $18.2M | 1.1% | +$937K |
| 31 | ERASERASCA INC | ADD | 1.1M | $17.9M | 1.1% | +$14.3M |
| 32 | DYNDYNE THERAPEUTICS INC | ADD | 972K | $17.6M | 1.0% | -$231K |
| 33 | CMPXCOMPASS THERAPEUTICS INC | TRIM | 3.3M | $17.5M | 1.0% | -$3.6M |
| 34 | ACRSACLARIS THERAPEUTICS INC | ADD | 4.5M | $16.8M | 1.0% | +$3.4M |
| 35 | TARSTARSUS PHARMACEUTICALS INC | TRIM | 225K | $15.8M | 0.9% | -$5.5M |
| 36 | MMEDMINIMED GROUP INC | NEW | 1.1M | $15.7M | 0.9% | new |
| 37 | ZLABZAI LAB LTD | ADD | 815K | $15.3M | 0.9% | +$1.0M |
| 38 | UNHUNITEDHEALTH GROUP INC | ADD | 53K | $14.3M | 0.8% | +$873K |
| 39 | CNTACENTESSA PHARMACEUTICALS PLC | ADD | 352K | $14.0M | 0.8% | +$5.9M |
| 40 | HTFLHEARTFLOW INC | ADD | 573K | $13.9M | 0.8% | +$5.8M |
| 41 | ARDXARDELYX INC | 2.3M | $13.8M | 0.8% | +$368K | |
| 42 | SMMTSUMMIT THERAPEUTICS INC | 710K | $13.5M | 0.8% | +$1.0M | |
| 43 | AZTAAZENTA INC | 569K | $12.0M | 0.7% | -$6.9M | |
| 44 | MLYSMINERALYS THERAPEUTICS INC | ADD | 440K | $11.9M | 0.7% | -$3.6M |
| 45 | DHRDANAHER CORP DEL | 62K | $11.7M | 0.7% | -$2.4M | |
| 46 | PTCTPTC THERAPEUTICS INC | ADD | 162K | $11.0M | 0.6% | +$6.3M |
| 47 | CAICARIS LIFE SCIENCES INC | TRIM | 563K | $10.1M | 0.6% | -$8.5M |
| 48 | ZBIOZENAS BIOPHARMA INC | 502K | $9.8M | 0.6% | -$8.4M | |
| 49 | BCAXBICARA THERAPEUTICS INC | ADD | 489K | $9.7M | 0.6% | +$2.5M |
| 50 | BBIOBRIDGEBIO PHARMA INC | ADD | 128K | $9.5M | 0.6% | +$1.6M |
| 51 | SLNOEURSOLENO THERAPEUTICS INC | ADD | 257K | $8.6M | 0.5% | -$2.8M |
| 52 | MBXMBX BIOSCIENCES INC | ADD | 288K | $8.6M | 0.5% | -$318K |
| 53 | TNGXTANGO THERAPEUTICS INC | 387K | $8.1M | 0.5% | +$4.7M | |
| 54 | REGNREGENERON PHARMACEUTICALS | 10K | $7.8M | 0.5% | +$8K | |
| 55 | IMNMIMMUNOME INC | 348K | $7.6M | 0.4% | +$136K | |
| 56 | AMLXAMYLYX PHARMACEUTICALS INC | 500K | $6.9M | 0.4% | +$910K | |
| 57 | OMDAOMADA HEALTH INC | TRIM | 541K | $6.8M | 0.4% | -$4.9M |
| 58 | INSPINSPIRE MED SYS INC | ADD | 132K | $6.8M | 0.4% | -$5.3M |
| 59 | APLSUSDAPELLIS PHARMACEUTICALS INC | ADD | 163K | $6.5M | 0.4% | +$2.8M |
| 60 | ALKERMES PLC | ADD | 184K | $6.5M | 0.4% | +$2.6M |
| 61 | EVHEVOLENT HEALTH INC | 2.7M | $6.1M | 0.4% | -$4.6M | |
| 62 | INDVINDIVIOR PHARMACEUTICALS INC | NEW | 200K | $6.1M | 0.4% | new |
| 63 | 430TERNS PHARMACEUTICALS INC | ADD | 114K | $6.0M | 0.4% | +$1.6M |
| 64 | EDAPEDAP TMS S A | ADD | 1.4M | $5.1M | 0.3% | +$894K |
| 65 | JANXJANUX THERAPEUTICS INC | ADD | 367K | $5.1M | 0.3% | +$150K |
| 66 | PHRPHREESIA INC | TRIM | 600K | $5.0M | 0.3% | -$9.8M |
| 67 | TMOTHERMO FISHER SCIENTIFIC INC | 10K | $4.9M | 0.3% | -$879K | |
| 68 | SYKSTRYKER CORPORATION | NEW | 15K | $4.9M | 0.3% | new |
| 69 | SIONSIONNA THERAPEUTICS INC | 99K | $4.0M | 0.2% | -$104K | |
| 70 | RCUSARCUS BIOSCIENCES INC | 180K | $3.9M | 0.2% | -$401K | |
| 71 | XBISPDR SERIES TRUST | TRIM | 30K | $3.8M | 0.2% | -$23.2M |
| 72 | ATECALPHATEC HLDGS INC | ADD | 350K | $3.8M | 0.2% | -$2.6M |
| 73 | PCVXVAXCYTE INC | ADD | 60K | $3.5M | 0.2% | +$1.3M |
| 74 | EYPTEYEPOINT INC | 259K | $3.3M | 0.2% | -$1.4M | |
| 75 | NVONOVO-NORDISK A S | NEW | 90K | $3.3M | 0.2% | new |
| 76 | OCULOCULAR THERAPEUTIX INC | ADD | 384K | $3.3M | 0.2% | -$948K |
| 77 | VKTXVIKING THERAPEUTICS INC | NEW | 96K | $3.1M | 0.2% | new |
| 78 | CYTKCYTOKINETICS INC | ADD | 45K | $3.0M | 0.2% | +$712K |
| 79 | IPSCCENTURY THERAPEUTICS INC | NEW | 1.3M | $2.9M | 0.2% | new |
| 80 | CVSCVS HEALTH CORP | NEW | 40K | $2.9M | 0.2% | new |
| 81 | ROIVANT SCIENCES LTD | ADD | 97K | $2.7M | 0.2% | +$761K |
| 82 | TLPHTALPHERA INC | 3.6M | $2.7M | 0.2% | -$1.4M | |
| 83 | OLMAOLEMA PHARMACEUTICALS INC | ADD | 170K | $2.5M | 0.1% | +$84K |
| 84 | SGRYSURGERY PARTNERS INC | TRIM | 208K | $2.5M | 0.1% | -$2.3M |
| 85 | LENZLENZ THERAPEUTICS INC | 257K | $2.4M | 0.1% | -$1.8M | |
| 86 | EWEDWARDS LIFESCIENCES CORP | TRIM | 29K | $2.3M | 0.1% | -$4.7M |
| 87 | DNTHDIANTHUS THERAPEUTICS INC | NEW | 27K | $2.2M | 0.1% | new |
| 88 | NGNENEUROGENE INC | 104K | $2.1M | 0.1% | -$46K | |
| 89 | AGLAGILON HEALTH INC | NEW | 260K | $2.1M | 0.1% | new |
| 90 | CORTCORCEPT THERAPEUTICS INC | 50K | $2.0M | 0.1% | +$277K | |
| 91 | ACHCACADIA HEALTHCARE COMPANY IN | TRIM | 76K | $1.8M | 0.1% | +$63K |
| 92 | TEVATEVA PHARMACEUTICAL INDS LTD | 46K | $1.4M | 0.1% | -$50K | |
| 93 | MLTXMOONLAKE IMMUNOTHERAPEUTICS | 62K | $1.2M | 0.1% | +$337K | |
| 94 | JAZZ PHARMACEUTICALS PLC | ADD | 6K | $1.1M | 0.1% | +$790K |
| 95 | JSPRJASPER THERAPEUTICS INC | 1.1M | $964K | 0.1% | -$1.0M | |
| 96 | LEGNLEGEND BIOTECH CORP | ADD | 41K | $733K | 0.0% | -$2K |
| 97 | GOSSGOSSAMER BIO INC | TRIM | 1.6M | $529K | 0.0% | -$9.6M |
| 98 | AM6AMICUS THERAPEUTIC | TRIM | 21K | $305K | 0.0% | -$27.2M |
| 99 | ORKAORUKA THERAPEUTICS INC | NEW | 4K | $202K | 0.0% | new |
| 100 | BCRXBIOCRYST PHARMACEUTICALS INC | NEW | 13K | $120K | 0.0% | new |
Source: SEC Form 13F. Values are as-of 2026-03-31 (quarter-end), not live. Percentages are of reported 13F value, not the fund’s full AUM (13F excludes shorts, cash, bonds, most non-US holdings).